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![Supramolecular host-guest nanosystems for overcoming cancer drug resistance](https://image.oaes.cc/4efd6ae6-5af4-4e3a-bb98-525baf37f9bb/cdr6077.fig.2.jpg)
Figure 2. (A) Schematic illustration of dual-drug co-loaded nanoparticle (Aa-DOX + ADD@PC) for overcoming cancer drug resistance; The expression levels of (B) P-gp and (C) XIAP in MCF-7/ADR cells with different treatments; (D) Tumor growth inhibition curves of tumor-bearing mice after various formulations. (*P < 0.05) This figure is quoted with permission from Wang et al.[59]. ADD: Mitochondrial inhibitor; DOX: doxorubicin; XIAP: X-linked inhibitor of apoptosis protein.