fig2
Figure 2. Adenosine Biosynthesis in Inflamed Tissues. The accumulation of extracellular ATP, driven by stress-induced conditions, stimulates extracellular ADO production by the enzymes CD39 and CD73. ADO binds four G protein-coupled receptors, A1, A2A, A2B, and A3. ADO: Adenosine; ADP: adenosine diphosphate; AMP: adenosine monophosphate; ATP: adenosine triphosphate.
