fig2

Figure 2. Co-injection of SC263 tumor cells with Matrigel in Rag2 KO mice did not result in sustained tumor growth. (A and B) Tumor kinetics after s.c. injection with 5 × 10⁶ SC263-S: (A) and SC263-R cells; (B) (n = 3); (C and D) Tumor kinetics after s.c. injection with 2 × 10⁶ SC263-S: (C) and SC263-R cells; (D) mixed with 25% Matrigel (n = 4); (E and F) Tumor kinetics after s.c. injection with 2 × 10⁶SC263-S: (E) and SC263-R cells; (F) mixed with 50% Matrigel (n = 4); (G and H) Tumor kinetics after s.c. injection with 1 × 10⁶ SC263-S: (G) and SC263-R cells; (H) mixed with 50% Matrigel (n = 4). Each line represents the data of one individual mouse. KO: Knock-out; -R: cetuximab-resistant HNSCC cell line; -S: cetuximab-sensitive HNSCC cell line; s.c.: subcutaneous.