fig3
Figure 3. A therapeutic strategy focused on metabolic vulnerabilities and nutrient addiction: the PPP metabolism. Effects of xCT on cell death in the absence (A) or presence (B) of GLUT inhibitors or PPP inhibitors. GLUT1/SLC2A1: Glucose transporter 1; NADPH: nicotinamide adenine dinucleotide phosphate; PPP: pentose phosphate pathway; xCT: cystine/glutamate antiporter SLC7A11.
