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![Harnessing the value of TCTP in breast cancer treatment resistance: an opportunity for personalized therapy](https://image.oaes.cc/8a221065-081d-4216-a0e0-cc95ac1b2f02/cdr-2023-21.fig.4.jpg)
Figure 4. TPT1/TCTP transcripts in BC and normal tissues. Boxplot from TPT1/TCTP RNAseq gene expression data of TCGA (upper panel) and METABRIC databases (Lower panel). (A) in normal tissue and primary breast cancer tissue; (B) in different PAM50 breast cancer subtypes; (C) in different stages of the tumor; (D) in metastatic (91 samples) vs. no metastatic tumors (59 samples); (E) in TP53 mutated tumors vs. TP53 wild-type tumors. BC: Breast cancers; MET: mesenchymal-epithelial transition; METABRIC: molecular taxonomy of breast cancer international consortium; TCGA: the cancer genome atlas; TCTP: translationally controlled tumor protein; TPT1: tumor protein, translationally-controlled 1.