fig8
From: Circular RNA circNCOA3 promotes tumor progression and anti-PD-1 resistance in colorectal cancer
![Circular RNA circNCOA3 promotes tumor progression and anti-PD-1 resistance in colorectal cancer](https://image.oaes.cc/d7df2f82-7452-4d7f-9e85-5698e3866523/cdr60151.fig.8.jpg)
Figure 8. Working model of the mechanism of circNCOA3 on CRC progression and PD-1 antibody treatment resistance. CircNCOA3 acts as a ceRNA by competitively sponging miR-203a-3p.1 to regulate the levels of CXCL1 and modulate the proliferation, invasion, and immune evasion of CRC cells. CRC: Colorectal cancer; PD-1: programmed cell death 1; ceRNA: competing endogenous RNA.