fig4
Figure 4. Effect of the docetaxel ritonavir combination in the docetaxel-resistant DU-145DOC10 cell line in the 3D clonogenic assay. (A) Concentration-effect curves showing a decrease of the docetaxel IC50 from 9.5 to 2.8 nM in the presence of 10 μM ritonavir; (B) Bliss Modeled T/C analysis shows synergistic effects at 10 μM ritonavir when combined with medium concentrations of docetaxel (3.16 and 10 nM).
