fig1

Figure 1. Indirect comparison of PFS with PARPi maintenance according to BRCA or HRD/LOH status in the main randomized phase 3 trials. In VELIA trial, PFS was calculated from the start of chemotherapy. ATHENA MONO: PFS in BRCA mutated population is not reached. BRCAmut: BRCA mutated; BRCAwt: BRCA wild type; HRD: homologous recombination deficiency; HRp: homologous recombination proficiency; LOH: loss of heterozygosity; PARPi: poly (ADP-ribose) polymerase inhibitors; PFS: progression-free survival; VELIA: PSF in HRD/BRCAwt not reported.