fig7

Multimodal 4-arylchromene derivatives with microtubule-destabilizing, anti-angiogenic, and MYB-inhibitory activities

Figure 7. Inhibition of MYB activity in HEK-293 cells containing the reporter plasmid pGL4-5xMRE(GG)-Myc and the expression vector for MYB-2KR, upon treatment with compounds 1B; 2A-C; and 2F (0.1-100 nM) for 16 h. IC50 values were calculated with at least four independent experiments using GraphPad Prism 9.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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