fig6

Multimodal 4-arylchromene derivatives with microtubule-destabilizing, anti-angiogenic, and MYB-inhibitory activities

Figure 6. Effects of 2A; 2B (50, 500 nM); 2C (50, 1000 nM); and 2F (50, 250 nM) on the SIV growth of zebrafish larvae (24 hpf) after treatment (48 h). Positive controls used axitinib (50, 500 nM). Negative controls used equivalent amounts of DMSO. The SIV area was quantified using ImageJ and expressed as mean ± SD of at least 20 zebrafish. The significance is expressed as n.s. P > 0.05; ***P < 0.001; ****P < 0.0001 against control (one-way ANOVA, with Dunnett´s multiple comparison test).

Cancer Drug Resistance
ISSN 2578-532X (Online)

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