fig2
![Molecular vulnerabilities and therapeutic resistance in hormone receptor positive and HER2 dependent breast cancer tumours](https://image.oaes.cc/9677304d-3c76-4737-9afe-ba4000823eb6/4769.fig.2.jpg)
Figure 2. A schematic diagram showing resistance mechanisms driven by upregulation of ERBB4 and CDK6 amplification (red circle signifies amplification) or alternative signalling via FGFR2/RTK’s and JNK signal transduction. Figure used from Griffiths et al.[15].