fig2
![Role of prostate cancer stem-like cells in the development of antiandrogen resistance](https://image.oaes.cc/c36eb177-b97c-4b99-81d7-ad7a67ecd468/4722.fig.2.jpg)
Figure 2. Signaling pathways regulating CSCs and the use of inhibitors in suppressing these pathways. These molecules thereof could be developed as potential therapeutics. The denotes in the figure are: Hedgehog signaling pathway (HH), notch intracellular domain (NICD), phosphorylation (P), smoothened (SMO), Wnt signaling pathways (Wnt), nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkBα), RELA Proto-Oncogene (RelA), Frizzled (FZD), casein kinase I (CKI), Axin (AXIN), APC Regulator of WNT Signaling Pathway (APC), Dishevelled (Dvl), Glycogen Synthase Kinase (GSK), IkappaB Kinase (IKK).