fig2
From: Adjuvant role of a T-type calcium channel blocker, TTA-A2, in lung cancer treatment with paclitaxel
Figure 2. (A) In the monolayer culture, a change in cell morphology was observed in the treatment groups (Groups II-V). Treated cells showed decreased cell density and changed morphology from epithelial form to an elongated or circular shape (solid black cells). (B) In the spheroid culture, all the spheroids had a comparable size of ~300 μm, indicating no treatment effect on reducing the spheroid size, regardless of treatment. Scale bar: 200 μm. I: negative control; II: PTX 10 nM; III: TTA-A2 50 nM; IV: TTA-A2 100 nM; V: PTX 10 nM + TTA-A2 100 nM. PTX: Paclitaxel.
