fig4
![ATP-binding cassette transporters at the zebrafish blood-brain barrier and the potential utility of the zebrafish as an <i>in vivo </i>model](https://image.oaes.cc/3334bb94-d594-4d60-bda0-d681ac056b7c/4066.fig.4.jpg)
Figure 4. Zebrafish ABCG2 homologs do not functionally mimic human ABCG2. Three-day cytotoxicity assays were performed with gedatolisib, THZ1, THZ531, mitoxantrone, SN-38, or topotecan on empty-vector-transfected HEK293 cells (Vector), or HEK293 cells that express human ABCG2 (R5), zebrafish Abcg2a (ZF Abcg2a), Abcg2b (ZF Abcg2b), Abcg2c (ZF Abcg2c), or zebrafish Abcg2d (ZF Abcg2d).