fig1

Figure 1. Mechanisms of treatment of EBV PTLD. Treatment options, which will all be discussed in further detail in this review, include reduction of immunosuppression, chemotherapy (including classical multi-agent lymphoma-based regimens as well as single agent anti-metabolite therapy), donor lymphocyte infusions, anti-CD20 monoclonal antibodies, cytotoxic T lymphocytes, proteasome inhibitors, histone deacetylase inhibitors, and checkpoint inhibitors. EBV: Epstein-Barr virus; PTLD: post-transplant lymphoproliferative disorder.