fig4
From: HDAC inhibitors with potential to overcome drug resistance in castration-resistant prostate cancer
Figure 4. Structures of new HDAC inhibitors with promising activities against CRPC. HDAC: Histone deacetylase; CRPC: castration-resistant prostate cancer; AR: androgen receptor; EGFR: epidermal growth factor receptor; PI3K: phosphatidylinositol 3-kinase.