fig2
From: HDAC inhibitors with potential to overcome drug resistance in castration-resistant prostate cancer
Figure 2. HDAC network and cellular effects of HDAC inhibitors in CRPC. HDAC: Histone deacetylase; HDACi: HDAC inhibitor; T: testosterone; Hsp90: heat shock protein 90; AR: androgen receptor; STAT3: signal transducer and activator of transcription 3; HMGA2: high mobility group AT-hook 2; EMT: epithelial-to-mesenchymal transition.