fig2

Figure 2. Cryo-transmission electron microscopy images of PLAD-MLP liposomes and related formulations. A, B: PL-MLP liposomes with ammonium Ald in the water phase before (A: PLA-MLP) and after (B: PLAD-MLP) Dox loading. Note the disorganized precipitates of Ald-Dox with few cases of rod formation; C, D: PL-MLP liposomes with ammonium sulfate in the water phase before (C: PL-MLP like) and after (D: PLD-MLP) Dox loading. Note the well-formed rods across the entire liposome