fig3

Figure 3. Bendamustine resistance probability in COO subtypes of patient cohorts. A: bendamustine REGS in ABC/GCB subtypes of DLBCL; B: bendamustine resistance probabilities using the bendamustine REGS in BAGS-DLBCL subtypes; C: bendamustine resistance probability using the REGS in BAGS-MM subtypes separately for each dataset; D: bendamustine resistance probability using the REGS in TC subclasses separately for each dataset. Significant differences between subtypes were tested using Kruskal-Wallis tests. DLBCL: diffuse large B-cell lymphoma; MM: multiple myeloma; BAGS: B-cell associated gene signature; REGS: resistance gene signature; COO: cell-of-origin; ABC: activated B-cell-like; GCB: germinal center B-cell-like