fig1

A bendamustine resistance gene signature in diffuse large B-cell lymphoma and multiple myeloma

Figure 1. Dose-response curves for the bendamustine screens in DLBCL and MM cell lines. A: dose-response curves for the 14 DLBCL cell lines (DB, FARAGE, HBL-1, MC-116, NU-DHL-1, NU-DUL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, RIVA, SU-DHL-5, SU-DHL-8, SU-DHL-10, and U-2932) and 11 MM cell lines (AMO-1, KMS-11, KMS-12-BM, KMS-12-PE, LP-1, MOLP-2, MOLP-8, NCI-H929, OPM-2, RPMI-8226, and U266); B: ranked 50% growth inhibition (GI50) corrected for individual growth rates of the cell lines with DLBCL cell lines to the left and MM cell lines to the right; C: ranked area under the positive part of the curve (AUC0) values corrected for individual growth rates of the cell lines with DLBCL cell lines to the left and MM cell lines to the right. DLBCL: diffuse large B-cell lymphoma; MM: multiple myeloma

Cancer Drug Resistance
ISSN 2578-532X (Online)

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