fig5
From: Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics
Figure 5. Extravasation and cell targeting. The abnormally wide fenestrations in the blood vessels and the lack of lymphatic drainage facilitates extravasation of NPs. Once in the tumour micro environment (TME), the targeting moiety of the NPs enable its interaction with the desired cells, providing active targeting. NPs: nanoparticles