fig4
From: Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics
![Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics](https://image.oaes.cc/ca7d21e9-ecf9-4748-aa88-c5c0536aa4f7/3786.fig.4.jpg)
Figure 4. Strong parallels between EMT activation and CSC formation. CSC phenotype is a bidirectional dynamic process. Most of the identified CSC markers are also found in cells with mesenchymal phenotype (e.g., CD44+/CD24-, SPARK, WNT, NOTCH, and ABCG). CSCs: cancer stem cells; EMT: mesenchymal transition