fig2
From: Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics
Figure 2. The tumours microenvironment is a heterogenic dynamic entity. It is composed of different cell types (differentiated cancer cells, cancer stem cells, normal stromal cells like fibroblasts, mesenchymal cells, and tumour-infiltrated immune cells). It is localised near the blood vessels to obtain the nutrients needed for its continued growth and survival