fig3
![3,3'-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and microRNAs](https://image.oaes.cc/05c820b5-e9ce-449b-af88-c0a231f43f23/3692.fig.3.jpg)
Figure 3. Structures of anti-tumor active 3,3’-diindolylmethane (DIM) derivatives (glycosides, tetraindole, and stabilized derivatives). Cell lines: A549 lung cancer, HeLa cervix cancer, MCF-7 breast cancer, PC3 prostate cancer, DU-145 prostate cancer, MiaPaCa-2 pancreas cancer, COLO-205 colon cancer, MDA-MB-231 breast cancer, SKOV-3 ovarian cancer, and HUVEC endothelial cells