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From:  Genomic stability at the coding regions of the multidrug transporter gene ABCB1: insights into the development of alternative drug resistance mechanisms in human leukemia cells
Genomic stability at the coding regions of the multidrug transporter gene <i>ABCB1</i>: insights into the development of alternative drug resistance mechanisms in human leukemia cells

Figure 5. Exonic sequence analysis of ABCB1 and representative ATP-binding cassette (ABC) transporter genes. A-E: histograms of variant allelic frequencies of exome sequencing data obtained from gnomAD v2.1. Only the allele frequency window between 0 to 0.001 is shown. Some representative alleles with a frequency greater than 0.001 are indicated by arrowheads; F: statistical analysis of validated exon variant numbers of gnomAD v2.1. in five ABC transporter genes with the percentage ratios between SNVs and MNVs indicated

Cancer Drug Resistance
ISSN 2578-532X (Online)
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