fig2

Figure 2. Rhodamine 123 (Rh-123) accumulation assays. A and B: Rh-123 accumulation in the presence or absence of cyclosporine (CsA) and PSC-833 (PSC) in K562, R7, RVC, and RDC cells. The mean values (columns) and standard deviations (bars) were calculated from three independent experiments, with the mean values labeled on the top of the histograms; C and D: Representative histograms of Rh-123 accumulation in R7, RVC and RDC cells in the presence of 1 µmol/L PSC-833 and 4 µmol/L CsA