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![The tumor microenvironment of pancreatic adenocarcinoma and immune checkpoint inhibitor resistance: a perplex relationship](https://image.oaes.cc/3e11b792-87d5-4fff-85a6-2cf69af96e5b/3644.fig.1.jpg)
Figure 1. The interaction between pancreatic cancer cells, stroma cells, and immune system. MHC: major histocompatibility complex; PD-L1: programmed death-ligand 1; CTLA4: cytotoxic T-lymphocyte-associated protein 4; CXCL12: C-X-C motif chemokine 12; IL-6: Interleukin 6; GM-CSF: granulocyte-macrophage colony-stimulating factor