fig2

Figure 2. Role of serine in biological processes in the cell. 3PG: 3-phosphoglycerate; PEP: phosphoenolpyruvate; PKM1/2: pyruvate kinase isoforms M1/M2; PHGDH: 3-phosphoglycerate dehydrogenase; 3-PHP: 3-phosphohydroxypyruvate; PSAT: phosphoserine aminotransferase; 3PS: 3-phosphoserine; PSPH: phosphoserine phosphatase; NAD⁺: nicotinamide adenine dinucleotide, oxidized; NADH: nicotinamide adenine dinucleotide, reduced; Glu: glutamate; αKG: α-ketoglutarate; SPT: serine palmitoyltransferase; SHMT1: serine hydroxymethyltransferase 1; 5,10-meTHF: 5,10-methylene tetrahydrofolate; mTHF: 5-methyl tetrahydrofolate; THF: tetrahydrofolate; GSH: reduced glutathione; HCY: homocysteine; SAH: S-adenosyl homocysteine; SAM: S-adenosyl methionine