fig1

Figure 1. Prostate cancer cell of origin and miRNA regulation. Schematic illustration showing the different cell types of the prostate gland contributing to the formation of CRPC and SCNC and the roles of miRNAs in the regulation of therapy-induced NE. miRNA: MicroRNA; CRPC: castration-resistant prostate cancer; SCNC: small cell neuroendocrine carcinoma; NE: neuroendocrine