fig2

ABCA1 is associated with the development of acquired chemotherapy resistance and predicts poor ovarian cancer outcome

Figure 2. Kaplan-Meier survival analysis showing relationship between ABC transporter protein expression and HGSOC patient progression-free survival (PFS). Median immunoreactive (IR) scores were used as cut-off points to separate samples into groups with low or high ABC transporter protein expression: (A) low ABCA1 expression (IR ≤ 8) vs. high ABCA1 expression (IR ≥ 9); (B) low ABCB1 expression (IR ≤ 2) vs. high ABCB1 expression (IR ≥ 3); (C) low ABCB3 expression (IR ≤ 8) vs. high ABCB3 expression (IR ≥ 9); (D) low ABCC2 expression (IR ≤ 11) vs. high ABCC2 expression (IR = 12); and (E) low ABCG2 expression (IR ≤ 9) vs. high ABCG2 expression (IR ≥ 10). Data were analyzed using log rank test. IR:Immunoreactive score.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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