fig7
![Imaging probes for non-invasive tumoral detection and functional monitoring of cancer multidrug resistance](https://image.oaes.cc/f7811102-d6e0-4e38-96e4-58de6fa9b7a2/3346.fig.7.jpg)
Figure 7. Cellular uptake of 99mTc-DMEOP, 99mTc-TMEOP, and 99mTc-Sestamibi in several human drug resistant cancer cell lines: MCF7 Pgp and H69 Lx4 overexpressing the Pgp protein and H69 AR overexpressing MRP1. For comparison, the uptake curves in the corresponding non-resistant cell lines, MCF7 and H69 (discontinuous lines), are also represented. The results are presented as the percentage of cell-associated radioactivity normalized to 106 cells over time, were calculated from independent biological replicates (n = 3-4), and are given as the average ± SEM. Pgp: P-glycoprotein; MRP1: multidrug-resistant protein 1