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Figure 1. Role of ALDH1A1 in cancer cells. ALDH1A1 regulates several hallmarks of cancer, strengthening its central role in tumor progression and malignancy. ALDH1A1: Aldehyde dehydrogenase 1A1; RA: retinoic acid; RAR: retinoic acid receptor; RXR: retinoic X receptor; ROS: reactive oxygen species