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From: Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targets
![Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targets](https://image.oaes.cc/9f4a45f2-d60b-4caa-943f-56019a197328/3153.fig.2.jpg)
Figure 2. Characteristic of CSCs contributing to higher drug resistance. Higher therapeutic resistance of CSCs is maintained by many features including quiescence, epithelial-to-mesenchymal transition, low ROS level, efficient drug efflux ability and upregulated survival signaling. CSCs: cancer stem-like cells