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From: Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targets
![Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targets](https://image.oaes.cc/9f4a45f2-d60b-4caa-943f-56019a197328/3153.fig.1.jpg)
Figure 1. Schematic model of CSC-derived recurrence and metastasis. CSCs are thought to possess high tumorigenic potential because they have the self-renewing activity and the potency to generate differentiated cell populations. CSCs also survive after treatment with chemotherapy or radiotherapy, which leads to recurrence and metastasis, two major causes of poor patient prognosis. CSCs: cancer stem-like cells