fig1
![Targeting the “undruggable” RAS - new strategies - new hope?](https://image.oaes.cc/f7093f2d-a388-46e2-9113-8e6e17920f86/3125.fig.1.jpg)
Figure 1. Amino acid sequences of RAS isoforms. The sequences of the RAS isoforms are compared and non-identical areas are marked by dashed rectangles. Amino acids 1-166 constitute the catalytic domain and amino acids 167-188/189 represent the hypervariable region. The amino acids are coloured based on their physico-chemical properties. Hydrophobic (black), polar/neutral (green), acidic (red) und basic (blue)