fig5
From: Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma
Figure 5. Effect of chemoresistance on serine isotopomer ratios. A: Model depicting the pathway for serine M2 and M3 isotopomer production from U-13C glucose; B: Serine M3:M2 isotopomer ratios in BCNU-sensitive (9L-S) and BCNU-resistant (9L-R) glioma cells in the absence and presence of 40 mM DCA. Bars (mean ± SD) with different letters are significantly different from each other at P ≤ 0.05
