fig4
From: Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma
Figure 4. Effect of chemoresistance on fumarate and succinate isotopomer ratios. Isotopomer ratios for (A) fumarate and (B) succinate in BCNU-sensitive (9L-S) and BCNU-resistant (9L-R) glioma cells in the absence and presence of 40 mM DCA. Bars (mean ± SD) with different letters are significantly different from each other at P ≤ 0.05
