fig1
From: Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma
![Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma](https://image.oaes.cc/fbb06c61-f02a-4138-a742-4ae4f2014e4d/3128.fig.1.jpg)
Figure 1. Development of BCNU-resistant 9L glioma cells. BCNU sensitive 9L glioma cells (9L-S) were grown in the presence of increasing concentrations of BCNU resulting in a 9L subculture that was BCNU-resistant (9L-R). Cell viability of 9L-S and 9L-R cells was quantified after exposure of both cell types to increasing concentrations of BCNU and expressed as percent survival (mean ± SD, n = 6). Significantly different from 9L-S at **P ≤ 0.01 and ****P ≤ 0.0001. BCNU: 1,3-bis (2-chloroethyl)-1-nitrosourea