fig8
![Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation](https://image.oaes.cc/111b0db9-132c-45f9-9530-02575fd741de/3424.fig.8.jpg)
Figure 8. In silico analysis of LRP promoter sequence: 1.5 kb promoter region of LRP region was retrieved from Ensembl database (www.ensembl.org) and putative NRF2 binding sites were predicted (consite.genereg.net) as indicated. A: lung resistance protein or major vault protein - 1.5 kb promoter region; B: putative transcription factor binding sites found along LRP promoter. Sequences highlighted in blue show NRF2 binding sites as predicted by ConSite and +1 indicates the transcriptional start site. NRF2: nuclear factor erythroid-derived 2-like 2; LRP: lung resistance protein