fig8

Figure 8. In silico analysis of LRP promoter sequence: 1.5 kb promoter region of LRP region was retrieved from Ensembl database (www.ensembl.org) and putative NRF2 binding sites were predicted (consite.genereg.net) as indicated. A: lung resistance protein or major vault protein - 1.5 kb promoter region; B: putative transcription factor binding sites found along LRP promoter. Sequences highlighted in blue show NRF2 binding sites as predicted by ConSite and +1 indicates the transcriptional start site. NRF2: nuclear factor erythroid-derived 2-like 2; LRP: lung resistance protein