fig1

Figure 1. Centrosome structure. A: the centrosome consists a pair of orthogonal centrioles, surrounded by mass proteins, referred to as the pericentriolar material (PCM). PCM proteins subdivide the PCM to three layers depending on diameter of the ring-like structures. Mother centrioles possess subdistal appendages and distal appendages; B: each centriole is a cylindrical structure with nine-fold microtubule organized like a central cartwheel. The triplet microtubules are composed of internal A, middle B, and external C microtubules. The figure is adapted and modified^[9]