fig2

Beyond dopamine: exploring endocannabinoids in Parkinson's disease

Figure 2. Expression of DAGLA, DAGLB, and MGLL in human SN region. Dot plot of a previously published single-nuclei transcriptomic dataset from the human SN region[66]. It compares the gene expression levels of DAGLA, DAGLB, and MGLL in type 1 and type 2 astrocytes, DANs, endothelial cells, GABAergic neurons, microglia, and type 1-3 oligodendrocytes, as well as OPCs. The size of each circle indicates the percentage of cells expressing a given gene within the cell population. The color intensity, ranging from light to dark red, represents the increase in gene expression level. DAGLA: Diacylglycerol lipase α; DAGLB: diacylglycerol lipase β; MGLL: monoacylglycerol lipase; SN: substantia nigra; DANs: nigrostriatal dopaminergic neurons; GABA: gamma-aminobutyric acid; OPCs: oligodendrocyte precursor cells.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)

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