fig6
![Fibril-forming motif of non-expanded ataxin-3 revealed by scanning proline mutagenesis](https://image.oaes.cc/b5720fb6-1f82-4c27-9f66-82a2d36fb250/and3015.fig.6.jpg)
Figure 6. The fibril-forming motif of the Josephin domain was identified based on FTIR measurements of ataxin-3(22Q) and proline mutations. FTIR of the following mutations: (A) ataxin-3(22Q); (B) ataxin-3(22Q)/F74P; (C) ataxin-3(22Q)/S81P; (D) ataxin-3(22Q)/N82P; (E) ataxin-3(22Q)/L89P; and (F) ataxin-3(22Q)/I92P. The experimental conditions are the same as those in Figure 4. FTIR: Fourier transform infrared spectroscopy.