fig1

Fibril-forming motif of non-expanded ataxin-3 revealed by scanning proline mutagenesis

Figure 1. Most of the hexapeptides of non-expanded ataxin-3 did not tend to form fibrils. Diagram of the 3D-profile Rosetta energies (y-axis) calculated for each six-residue segment from the ataxin-3 sequence (x-axis). Segments predicted to form fibrils are highlighted in red.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)

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