fig3

Figure 3. Structural analytes. (A and B) Nf-L was not elevated in the sera of studied cross-sectional patients, but was elevated in rapidly progressing patients compared with slowly progressing patients; Nf-L was not elevated in both rapidly and slowly progressing patients compared with HC; (C and D) pNf-H was not elevated in cross-sectionally studied patients compared with HC, but was decreased in rapidly progressing patients compared with HC; there was no difference in pNf-H levels between slowly progressing patients and HC; (E - G) There was a weak correlation between Nf-L and disease progression, but there was a negative correlation between pNf-H and disease progression; Nf-L and pNf-H did not correlate with each other. * P < 0.05, *** P < 0.001, and n.s.: not significant.