fig9

Selective expression of neurodegenerative diseases-related mutant p150<sup>Glued</sup> in midbrain dopaminergic neurons causes progressive degeneration of nigrostriatal pathway

Figure 9. Co-localization of lysosomes with G59S mutation-induced p150Glued aggregates and upregulated ubiquitination in the dystrophic DA neurites of G59S Tg mice. (A) Immunofluorescent images show the staining of p150Glued and p135+ (purple), TH (red), and LAMP2 (green) in the SNr of six-month-old nTg and G59S Tg mice. Scale bar: 20 μm. (B) Immunofluorescent images show the staining of p150Glued and p135+ (purple), TH (red), and ubiquitin (green) in the SNr of six-month-old nTg and G59S Tg mice. Scale bar: 20 μm.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)

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