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![Pneumonia promotes pulmonary metastasis of HCC after transplantation via VEGF regulated PI3K/AKT/Cas-9 signaling and angiogenesis](https://image.oaes.cc/6ede9cd6-6ddf-4fc3-83b1-36b479419f14/hr4050.fig.3.jpg)
Figure 3. VEGF was originated from macrophage. (A) Concentration of VEGF in supernatants of THP-1-derived macrophages, lung fibroblast cell line HFL-1, and lung epithelium-derived adenocarcinoma cell line A549 stimulated with LPS or not; (B) Immunohistochemistry staining of VEGF of lungs in the control or macrophage-depleted mice.