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![Genomic alterations in intrahepatic cholangiocarcinoma](https://image.oaes.cc/cb5cb83e-3ba9-4b5b-9ea7-79180f3d57da/hr9037.fig.1.jpg)
Figure 1. Genetic alterations in iCCA. Multi-omic analyses of large patient cohorts have revealed the most prevalent alterations in iCCA. FGFR2 fusions and mutations in IDH1/2 are the most prevalent, while alterations in KRAS, ARID1A, CDKN2A/B, and BAP1 occur at slightly lower frequencies. Other alterations occur in iCCA at low frequencies but are still considered actionable therapeutic targets are herein depicted. Created with https://www.biorender.com/ .