fig5

Figure 5. Schematic representation of the novel-designed 3D co-culture system and our experimental design (A) Created with BioRender.com. Expression analysis of inflammation- and fibrogenesis-related markers CXCR4 (B) IL1B (C) FAS (D) and TGFB1 (E) upon MM treatment compared to the control group (Unpaired t-test, * P < 0.05, **P < 0.01, ***P < 0.001). CXCR4: C-X- Motif Chemokine Receptor 4; IL1B: Interleukin 1 Beta; FAS: fas Cell Surface Dearth Receptor; TGFB1: Transforming Growth Factor Beta 1.