fig2
Figure 2. Interactions of cells involved in cholangiocarcinoma development and tumor microenvironment. The green arrows indicate induction, while the red dotted lines suggest inhibition. CCA: cholangiocarcinoma; PD-1: programmed cell death; CTLA4: cytotoxic T-lymphocyte-associated protein 4; FasL: Fas ligand; KIR: killer cell immunoglobulin-like receptor; NKs: natural killers; IL-10: interleukin-10; TGFβ: transforming growth factor β; MDSCs: myeloid-derived suppressor cells; PD-L1: programmed cell death ligand;