fig6
![Combined hepatocellular-cholangiocarcinoma: morpho-molecular updates and considerations](https://image.oaes.cc/44fb2f17-9b24-4c6e-bdb4-782254355667/5678.fig.6.jpg)
Figure 6. Case of cHCC-CCA with features of biliary adenofibroma. (A) Gross features of the 2.5 cm nodule with yellow-greyish color, in an HBV-positive patient with S3 fibrosis. (B) H&E, 10x, areas resembling ductal plate malformation (DPM). (C) H&E, 10x, areas resembling biliary adenofibroma. (D) H&E 40x, Peculiar neoplastic glandular component (blu arrow) with intraglandular growth of HCC (green arrow), confirmed by IHC with arginase-1. (E) 20x (green arrow).